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JULY 21, 2025

Adjuvant Fosaprepitant Found to Decrease PONV in Bariatric Surgery Patients

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Megan Wang, MD

NEW YORK—Prophylactic treatment with the neurokinin-1 receptor antagonist fosaprepitant, when combined with a standardized antiemetic regimen comprising dexamethasone and ondansetron, is superior to standard treatment alone in decreasing postoperative nausea and vomiting (PONV) and rescue antiemetic requirements in patients undergoing bariatric surgery, a new study has concluded.

“PONV is a common complication in any type of surgery, but in bariatric surgery it’s