By Thomas Rosenthal

Continuing antimicrobial regimens after surgery does not decrease surgical site infections but may increase acute kidney injuries and Clostridioides difficile infections, according to a new study.

The optimum time to administer antimicrobial surgical prophylaxis is an hour before the procedure and during the surgery, whereas the best time to stop the regimen is within 24 hours after skin closure, said Westyn Branch-Elliman, MD, MMSc, an assistant professor of medicine at